Trimethoprim and Sulphamethoxazole in Typhoid Fever in Children

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Trimethoprim and sulphamethoxazole in typhoid fever in children.

One hundred and three children with proved typhoid fever were treated with trimethoprim-sulphamethoxazole, and the results compared with those of a further 40 children treated with chloramphenicol. The bacteriological response to trimethoprim-sulphamethoxazole was unsatisfactory. From this study it seems that at present chloramphenicol is still the treatment of choice for typhoid fever. In view...

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Effect of trimethoprim-sulphamethoxazole on typhoid and salmonella carriers.

Four chronic typhoid carriers from the Aberdeen typhoid outbreak of 1964 were treated with trimethoprim-sulphamethoxazole. The male carrier remained clear of infection following treatment but the three female carriers, all with gall bladder abnormalities, remained excretors. A convalescent typhoid excretor also remained clear of infection after treatment as well as two other salmonella carriers...

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HEMOPHAGOCYTIC SYNDROME IN TYPHOID FEVER AND BRUCELLOSIS

Hemophagocytic syndrome is a non-malignant process that is characterized clinically by fever, hepatomegaly, splenomegaly, pancytopenia in peripheral blood, and reactive histiocytes in the bone marrow. Bacterial infectious diseases like typhoid fever and brucellosis and viral infections including CMV, herpes viruses, and Epstein-Barr virus are diagnosed as the cause of this syndrome. In thi...

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Trimethoprim-sulphamethoxazole in enteric fevers.

Clinical improvement was rapid in all 13 patients with enteric fever and one with Brucella abortus infection treated with trimethoprim-sulphamethoxazole. There were no side-effects of the treatment and it was found easy to administer to toxic and delirious patients.

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ژورنال

عنوان ژورنال: BMJ

سال: 1971

ISSN: 0959-8138,1468-5833

DOI: 10.1136/bmj.3.5777.738